Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies
<p style="text-align:justify;">Adenovirus is a widely used vector for cancer gene therapy because of its high infection efficiency and capacity for transgene expression in both dividing and nondividing cells. However, neutralisation of adenovirus by pre-existing antibodies can lead t...
المؤلفون الرئيسيون: | Fisher, K, Stallwood, Y, Green, N, Ulbrich, K, Mautner, V, Seymour, L |
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التنسيق: | Journal article |
منشور في: |
Springer Nature
2001
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مواد مشابهة
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Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA.
حسب: Carlisle, R, وآخرون
منشور في: (2006) -
Retargeting polymer-coated adenovirus to the FGF receptor allows productive infection and mediates efficacy in a peritoneal model of human ovarian cancer.
حسب: Green, N, وآخرون
منشور في: (2008) -
Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor.
حسب: Morrison, J, وآخرون
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Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera.
حسب: Carlisle, R, وآخرون
منشور في: (2008) -
Retargeting adenovirus gene therapy via the epidermal growth factor receptor
حسب: Morrison, J, وآخرون
منشور في: (2006)