Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies
<p style="text-align:justify;">Adenovirus is a widely used vector for cancer gene therapy because of its high infection efficiency and capacity for transgene expression in both dividing and nondividing cells. However, neutralisation of adenovirus by pre-existing antibodies can lead t...
Κύριοι συγγραφείς: | Fisher, K, Stallwood, Y, Green, N, Ulbrich, K, Mautner, V, Seymour, L |
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Μορφή: | Journal article |
Έκδοση: |
Springer Nature
2001
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera.
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Retargeting adenovirus gene therapy via the epidermal growth factor receptor
ανά: Morrison, J, κ.ά.
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