T helper cell unresponsiveness: rapid induction in antigen-transgenic and reversion in non-transgenic mice.
T cell tolerance is usually established by clonal deletion of self-specific T cells in the thymus, or some times, in the periphery. Alternatively, tolerance may also be achieved by induction of clonal T cell unresponsiveness by a poorly understood mechanism called "anergy". We found that t...
Autors principals: | , , , , , , , |
---|---|
Format: | Journal article |
Idioma: | English |
Publicat: |
1994
|