T helper cell unresponsiveness: rapid induction in antigen-transgenic and reversion in non-transgenic mice.
T cell tolerance is usually established by clonal deletion of self-specific T cells in the thymus, or some times, in the periphery. Alternatively, tolerance may also be achieved by induction of clonal T cell unresponsiveness by a poorly understood mechanism called "anergy". We found that t...
Main Authors: | Bachmann, M, Rohrer, U, Steinhoff, U, Bürki, K, Skuntz, S, Arnheiter, H, Hengartner, H, Zinkernagel, R |
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Format: | Journal article |
Language: | English |
Published: |
1994
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