HIV-1 down-regulates the expression of CD1d via Nef.
HIV-1 has evolved several strategies to subvert host immune responses to the infected cells. One is to inhibit CTL recognition by HIV-1 Nef-mediated down-regulation of MHC-I expression on the surface of infected cells. Here we report that Nef also reduces the expression of the non-classical MHC-I li...
Những tác giả chính: | Chen, N, McCarthy, C, Drakesmith, H, Li, D, Cerundolo, V, Mcmichael, A, Screaton, G, Xu, X |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2006
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