High-level production and optimization of monodispersity of 11beta-hydroxysteroid dehydrogenase type 1.

High-level production and optimization of monodispersity of 11beta-hydroxysteroid dehydrogenase type 1.

11beta-Hydroxysteroid dehydrogenase type 1 (11beta-HSD1) is an intraluminally oriented, endoplasmic reticulum (ER)-bound enzyme catalyzing the interconversion between inactive cortisone and hormonally active cortisol. Heterologous production of 11beta-HSD1, devoid of its N-terminal transmembrane seg...

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Bibliographic Details
Main Authors:	Elleby, B, Svensson, S, Wu, X, Stefansson, K, Nilsson, J, Hallén, D, Oppermann, U, Abrahmsén, L
Format:	Journal article
Language:	English
Published:	2004

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