ICAM-1 co-stimulates target cells to facilitate antigen presentation.
Adhesion molecules are known to mediate cell-cell interactions, particularly those between T cells and antigen-presenting or target cells. Recent studies identified ICAM-1 as a co-stimulatory ligand that binds to lymphocyte function associated antigen-1 (LFA-1), thereby promoting the activation of T...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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