ICAM-1 co-stimulates target cells to facilitate antigen presentation.

Adhesion molecules are known to mediate cell-cell interactions, particularly those between T cells and antigen-presenting or target cells. Recent studies identified ICAM-1 as a co-stimulatory ligand that binds to lymphocyte function associated antigen-1 (LFA-1), thereby promoting the activation of T...

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Những tác giả chính: Lebedeva, T, Dustin, M, Sykulev, Y
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2005