PYY-dependent restoration of impaired insulin and glucagon secretion in type-2 diabetes following Roux-En-Y gastric bypass surgery

PYY-dependent restoration of impaired insulin and glucagon secretion in type-2 diabetes following Roux-En-Y gastric bypass surgery

Roux-en-Y gastric bypass (RYGB) is a weight-reduction procedure resulting in rapid resolution of type-2 diabetes (T2D). The role of pancreatic islet function in this restoration of normoglycemia has not been fully elucidated. Using the diabetic GK rat model, we demonstrate that RYGB restores normal...

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Bibliographic Details
Main Authors:	Ramracheya, R, McCulloch, L, Clark, A, Wiggins, D, Johannessen, H, Olsen, M, Cai, X, Zhao, C, Chen, D, Rorsman, P
Format:	Journal article
Published:	Cell Press 2016

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