Effects of non-physiological blood pressure artefacts on cerebral autoregulation
Cerebral autoregulation refers to the brain's regulation mechanisms that aim to maintain the cerebral blood flow approximately constant. It is often assessed by the autoregulation index (ARI). ARI uses arterial blood pressure and cerebral blood flow velocity time series to produce a ten-scale i...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Elsevier
2017
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| _version_ | 1797061990735151104 |
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| author | Mahdi, A Rutter, E Payne, S |
| author_facet | Mahdi, A Rutter, E Payne, S |
| author_sort | Mahdi, A |
| collection | OXFORD |
| description | Cerebral autoregulation refers to the brain's regulation mechanisms that aim to maintain the cerebral blood flow approximately constant. It is often assessed by the autoregulation index (ARI). ARI uses arterial blood pressure and cerebral blood flow velocity time series to produce a ten-scale index of autoregulation performance (0 denoting the absence of and 9 the strongest autoregulation). Unfortunately, data are rarely free from various artefacts. Here, we consider four of the most common non-physiological blood pressure artefacts (saturation, square wave, reduced pulse pressure and impulse) and study their effects on ARI for a range of different artefact sizes. We show that a sufficiently large saturation and square wave always result in ARI reaching the maximum value of 9. The pulse pressure reduction and impulse artefact lead to more diverse behaviour. Finally, we characterized the critical size of artefacts, defined as the minimum artefact size that, on average, leads to a 10% deviation of ARI. |
| first_indexed | 2024-03-06T20:39:07Z |
| format | Journal article |
| id | oxford-uuid:33abb2ed-be2e-4648-9053-8a35894c1786 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:39:07Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:33abb2ed-be2e-4648-9053-8a35894c17862022-03-26T13:21:32ZEffects of non-physiological blood pressure artefacts on cerebral autoregulationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:33abb2ed-be2e-4648-9053-8a35894c1786EnglishSymplectic Elements at OxfordElsevier2017Mahdi, ARutter, EPayne, SCerebral autoregulation refers to the brain's regulation mechanisms that aim to maintain the cerebral blood flow approximately constant. It is often assessed by the autoregulation index (ARI). ARI uses arterial blood pressure and cerebral blood flow velocity time series to produce a ten-scale index of autoregulation performance (0 denoting the absence of and 9 the strongest autoregulation). Unfortunately, data are rarely free from various artefacts. Here, we consider four of the most common non-physiological blood pressure artefacts (saturation, square wave, reduced pulse pressure and impulse) and study their effects on ARI for a range of different artefact sizes. We show that a sufficiently large saturation and square wave always result in ARI reaching the maximum value of 9. The pulse pressure reduction and impulse artefact lead to more diverse behaviour. Finally, we characterized the critical size of artefacts, defined as the minimum artefact size that, on average, leads to a 10% deviation of ARI. |
| spellingShingle | Mahdi, A Rutter, E Payne, S Effects of non-physiological blood pressure artefacts on cerebral autoregulation |
| title | Effects of non-physiological blood pressure artefacts on cerebral autoregulation |
| title_full | Effects of non-physiological blood pressure artefacts on cerebral autoregulation |
| title_fullStr | Effects of non-physiological blood pressure artefacts on cerebral autoregulation |
| title_full_unstemmed | Effects of non-physiological blood pressure artefacts on cerebral autoregulation |
| title_short | Effects of non-physiological blood pressure artefacts on cerebral autoregulation |
| title_sort | effects of non physiological blood pressure artefacts on cerebral autoregulation |
| work_keys_str_mv | AT mahdia effectsofnonphysiologicalbloodpressureartefactsoncerebralautoregulation AT ruttere effectsofnonphysiologicalbloodpressureartefactsoncerebralautoregulation AT paynes effectsofnonphysiologicalbloodpressureartefactsoncerebralautoregulation |