High affinity streptococcal binding to human fibronectin requires specific recognition of sequential F1 modules.
Fibronectin (Fn) binding by the Streptococcus pyogenes protein SfbI has been shown to trigger integrin-dependent internalization of this pathogen by human epithelial and endothelial cells. Here, using nuclear magnetic resonance spectroscopy and isothermal titration calorimetry in a dissection approa...
Hoofdauteurs: | , , , , , , |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
2004
|