High affinity streptococcal binding to human fibronectin requires specific recognition of sequential F1 modules.

Fibronectin (Fn) binding by the Streptococcus pyogenes protein SfbI has been shown to trigger integrin-dependent internalization of this pathogen by human epithelial and endothelial cells. Here, using nuclear magnetic resonance spectroscopy and isothermal titration calorimetry in a dissection approa...

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Bibliografische gegevens
Hoofdauteurs: Schwarz-Linek, U, Pilka, E, Pickford, A, Kim, J, Höök, M, Campbell, I, Potts, JR
Formaat: Journal article
Taal:English
Gepubliceerd in: 2004