Review: Diagnosis of scrub typhus

Scrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of th...

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Hauptverfasser: Koh, G, Maude, R, Paris, D, Newton, P, Blacksell, S
Format: Journal article
Sprache:English
Veröffentlicht: 2010
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author Koh, G
Maude, R
Paris, D
Newton, P
Blacksell, S
author_facet Koh, G
Maude, R
Paris, D
Newton, P
Blacksell, S
author_sort Koh, G
collection OXFORD
description Scrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of the diagnosis, usually by indirect fluorescent antibody (IFA) assay. We discuss the limitations of IFA, debate the value of other methods based on antigen detection and nucleic acid amplification, and outline recommendations for future study. Copyright © 2010 by The American Society of Tropical Medicine and Hygiene.
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spelling oxford-uuid:33b02a1e-8a6b-41a8-878b-dbc5391d08502022-03-26T13:21:31ZReview: Diagnosis of scrub typhusJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:33b02a1e-8a6b-41a8-878b-dbc5391d0850EnglishSymplectic Elements at Oxford2010Koh, GMaude, RParis, DNewton, PBlacksell, SScrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of the diagnosis, usually by indirect fluorescent antibody (IFA) assay. We discuss the limitations of IFA, debate the value of other methods based on antigen detection and nucleic acid amplification, and outline recommendations for future study. Copyright © 2010 by The American Society of Tropical Medicine and Hygiene.
spellingShingle Koh, G
Maude, R
Paris, D
Newton, P
Blacksell, S
Review: Diagnosis of scrub typhus
title Review: Diagnosis of scrub typhus
title_full Review: Diagnosis of scrub typhus
title_fullStr Review: Diagnosis of scrub typhus
title_full_unstemmed Review: Diagnosis of scrub typhus
title_short Review: Diagnosis of scrub typhus
title_sort review diagnosis of scrub typhus
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