Differential regulation of type I and type II interleukin-1 receptors in focal brain inflammation.
Most pathologies of the brain have an inflammatory component, associated with the release of cytokines such as interleukin-1beta (IL-1beta) from resident and infiltrating cells. The IL-1 type I receptor (IL-1RI) initiates a signalling cascade but the type II receptor (IL-1RII) acts as a decoy recept...
| Main Authors: | , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2005
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