Differential regulation of type I and type II interleukin-1 receptors in focal brain inflammation.

Differential regulation of type I and type II interleukin-1 receptors in focal brain inflammation.

Most pathologies of the brain have an inflammatory component, associated with the release of cytokines such as interleukin-1beta (IL-1beta) from resident and infiltrating cells. The IL-1 type I receptor (IL-1RI) initiates a signalling cascade but the type II receptor (IL-1RII) acts as a decoy recept...

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Bibliographic Details
Main Authors: Docagne, F, Campbell, S, Bristow, A, Poole, S, Vigues, S, Guaza, C, Perry, V, Anthony, D
Format: Journal article
Language:English
Published: 2005

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