A common variant associated with dyslexia reduces expression of the KIAA0319 gene.

A common variant associated with dyslexia reduces expression of the KIAA0319 gene.

Numerous genetic association studies have implicated the KIAA0319 gene on human chromosome 6p22 in dyslexia susceptibility. The causative variant(s) remains unknown but may modulate gene expression, given that (1) a dyslexia-associated haplotype has been implicated in the reduced expression of KIAA0...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Dennis, M, Paracchini, S, Scerri, T, Prokunina-Olsson, L, Knight, J, Wade-Martins, R, Coggill, P, Beck, S, Green, E, Monaco, A
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	Public Library of Science 2009

Παρόμοια τεκμήρια

A common variant associated with dyslexia reduces expression of the KIAA0319 gene.
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Έκδοση: (2009-03-01)

Expression of the KIAA0319 gene from a haplotype associated with developmental dyslexia
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Έκδοση: (2006)

Further evidence that KIAA0319 is associated with developmental dyslexia
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Έκδοση: (2006)

Alternative splicing in the dyslexia-associated gene KIAA0319.
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Έκδοση: (2007)

Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia.
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Έκδοση: (2006)

Association of the KIAA0319 dyslexia susceptibility gene with reading skills in the general population.
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Functional characterisation of dyslexia-susceptibility candidate genes KIAA0319 and KIAA0319L
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Linkage disequilibrium structure of KIAA0319 and DCDC2, two candidate susceptibility genes for developmental dyslexia
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The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration.
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Έκδοση: (2006)

The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration
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Έκδοση: (2006)

DCDC2, KIAA0319 and CMIP are associated with reading-related traits
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DCDC2, KIAA0319 and CMIP are associated with reading-related traits.
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The dyslexia-associated gene KIAA0319 encodes highly N- and O-glycosylated plasma membrane and secreted isoforms.
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Knockout mice for dyslexia susceptibility gene homologs KIAA0319 and KIAA0319L have unaffected neuronal migration but display abnormal auditory processing
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The Dyslexia-susceptibility protein KIAA0319 inhibits axon growth through Smad2 signaling.
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Έκδοση: (2009)

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Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development
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Έκδοση: (2022-08-01)

KIAA0319 influences cilia length, cell migration and mechanical cell–substrate interaction
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Έκδοση: (2022-01-01)

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Έκδοση: (2023-06-01)

PCSK6 is associated with handedness in individuals with dyslexia
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PCSK6 is associated with handedness in individuals with dyslexia.
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Έκδοση: (2011)

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Endosomal trafficking defects in patient cells with KIAA1109 biallelic variants
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Έκδοση: (2019-03-01)

Identification of candidate genes for dyslexia susceptibility on chromosome 18.
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Έκδοση: (2010-10-01)

Analysis of dyslexia candidate genes in the Raine cohort representing the general Australian population
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Έκδοση: (2011)

Analysis of dyslexia candidate genes in the Raine cohort representing the general Australian population.
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Έκδοση: (2011)

Correction: Identification of Candidate Genes for Dyslexia Susceptibility on Chromosome 18.
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Έκδοση: (2010-01-01)

KIAA1109 variants are associated with a severe disorder of brain development and arthrogryposis
ανά: Roechert, Bernd, κ.ά.
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New recombinant T. pallidum antigens Tp0453 and Tp0319 in the diagnostics of syphilis
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