Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog
Background. A novel fluorescent cAMP analog (8-[Pharos-575]- adenosine-3′, 5′-cyclic monophosphate) was characterized with respect to its spectral properties, its ability to bind to and activate three main isoenzymes of the cAMP-dependent protein kinase (PKA-Iα, PKA-IIα, PKA-IIβ) in vitro, its stabi...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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