Offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds.

OBJECTIVE: To compare offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds. METHOD: A total of 4800 randomly selected women in England were sent a survey three months after they had given birth; 2960 women responded. Odds ratios (OR) for rep...

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Main Authors: Rowe, R, Puddicombe, D, Hockley, C, Redshaw, M
Format: Journal article
Language:English
Published: 2008
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author Rowe, R
Puddicombe, D
Hockley, C
Redshaw, M
author_facet Rowe, R
Puddicombe, D
Hockley, C
Redshaw, M
author_sort Rowe, R
collection OXFORD
description OBJECTIVE: To compare offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds. METHOD: A total of 4800 randomly selected women in England were sent a survey three months after they had given birth; 2960 women responded. Odds ratios (OR) for reported offer and uptake of screening comparing women by area deprivation and ethnicity were calculated. RESULTS: In all, 65% of women reported having screening; 89% reported being offered screening, and 69% of these reported taking up the offer. There was no evidence of a difference in the reported offer (adjusted OR = 0.88, 95% confidence interval (CI) 0.65-1.19, p = 0.41) or uptake (adjusted OR = 0.84, 95% CI 0.66-1.06, p = 0.15) of screening for women living in the most deprived areas compared with other women. Asian women were less likely to report being offered screening than White women (adjusted OR = 0.61, 95% CI 0.39-0.94, p = 0.02) and were less likely to take up screening when offered (adjusted OR = 0.48, 95% CI 0.33-0.72, p < 0.001). CONCLUSIONS: While most pregnant women in England are offered prenatal screening for Down syndrome, approximately 1 in 10 is not. Asian women are less likely than White women to report being offered Down syndrome screening and are less likely to have a screening test when offered.
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spelling oxford-uuid:33c88b53-677a-4393-9f3b-d8013a68940a2022-03-26T13:22:14ZOffer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:33c88b53-677a-4393-9f3b-d8013a68940aEnglishSymplectic Elements at Oxford2008Rowe, RPuddicombe, DHockley, CRedshaw, M OBJECTIVE: To compare offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds. METHOD: A total of 4800 randomly selected women in England were sent a survey three months after they had given birth; 2960 women responded. Odds ratios (OR) for reported offer and uptake of screening comparing women by area deprivation and ethnicity were calculated. RESULTS: In all, 65% of women reported having screening; 89% reported being offered screening, and 69% of these reported taking up the offer. There was no evidence of a difference in the reported offer (adjusted OR = 0.88, 95% confidence interval (CI) 0.65-1.19, p = 0.41) or uptake (adjusted OR = 0.84, 95% CI 0.66-1.06, p = 0.15) of screening for women living in the most deprived areas compared with other women. Asian women were less likely to report being offered screening than White women (adjusted OR = 0.61, 95% CI 0.39-0.94, p = 0.02) and were less likely to take up screening when offered (adjusted OR = 0.48, 95% CI 0.33-0.72, p < 0.001). CONCLUSIONS: While most pregnant women in England are offered prenatal screening for Down syndrome, approximately 1 in 10 is not. Asian women are less likely than White women to report being offered Down syndrome screening and are less likely to have a screening test when offered.
spellingShingle Rowe, R
Puddicombe, D
Hockley, C
Redshaw, M
Offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds.
title Offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds.
title_full Offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds.
title_fullStr Offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds.
title_full_unstemmed Offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds.
title_short Offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds.
title_sort offer and uptake of prenatal screening for down syndrome in women from different social and ethnic backgrounds
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AT hockleyc offeranduptakeofprenatalscreeningfordownsyndromeinwomenfromdifferentsocialandethnicbackgrounds
AT redshawm offeranduptakeofprenatalscreeningfordownsyndromeinwomenfromdifferentsocialandethnicbackgrounds