Optimal translational termination requires C4 lysyl hydroxylation of eRF1.

Efficient stop codon recognition and peptidyl-tRNA hydrolysis are essential in order to terminate translational elongation and maintain protein sequence fidelity. Eukaryotic translational termination is mediated by a release factor complex that includes eukaryotic release factor 1 (eRF1) and eRF3. T...

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Dettagli Bibliografici
Autori principali:	Feng, T, Yamamoto, A, Wilkins, SE, Sokolova, E, Yates, L, Münzel, M, Singh, P, Hopkinson, R, Fischer, R, Cockman, M, Shelley, J, Trudgian, D, Schödel, J, McCullagh, J, Ge, W, Kessler, B, Gilbert, R, Frolova, L, Alkalaeva, E, Ratcliffe, P, Schofield, C, Coleman, M
Natura:	Journal article
Lingua:	English
Pubblicazione:	2014

Optimal translational termination requires C4 lysyl hydroxylation of eRF1.

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