Diverse mechanisms of IRF5 action in inflammatory responses

Interferon regulatory factor 5 (IRF5) is a key signal-dependent transcription factor in myeloid cells. Its expression is induced by granulocyte-macrophage colony stimulating factor and interferon-gamma. IRF5 protein is further activated in response to stimulation, translocating to the nucleus where...

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Hlavní autoři: Khoyratty, T, Udalova, I
Médium: Journal article
Jazyk:English
Vydáno: Elsevier 2018