Diverse mechanisms of IRF5 action in inflammatory responses
Interferon regulatory factor 5 (IRF5) is a key signal-dependent transcription factor in myeloid cells. Its expression is induced by granulocyte-macrophage colony stimulating factor and interferon-gamma. IRF5 protein is further activated in response to stimulation, translocating to the nucleus where...
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格式: | Journal article |
语言: | English |
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Elsevier
2018
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