An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme
<p><strong>Objective </strong>To develop methods to model the relationship between cancer detection and recall rates to inform professional standards.</p> <p><strong>Methods </strong>Annual screening programme information for each of the 80 English NHSBSP un...
| Main Authors: | , , , , , |
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| פורמט: | Journal article |
| שפה: | English |
| יצא לאור: |
Springer
2019
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| _version_ | 1826266506353180672 |
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| author | Blanks, R Given-Wilson, R Cohen, S Patnick, J Alison, R Wallis, M |
| author_facet | Blanks, R Given-Wilson, R Cohen, S Patnick, J Alison, R Wallis, M |
| author_sort | Blanks, R |
| collection | OXFORD |
| description | <p><strong>Objective </strong>To develop methods to model the relationship between cancer detection and recall rates to inform professional standards.</p> <p><strong>Methods </strong>Annual screening programme information for each of the 80 English NHSBSP units (totalling 11.3 million screening tests) for the seven screening years from 1 April 2009 to 31 March 2016 and some Dutch screening programme information were used to produce linear and non-linear models. The non-linear models estimated the modelled maximum values (MMV) for cancers detected at different grades and estimated how rapidly the MMV was reached (the modelled ‘slope’ (MS)). Main outcomes include the detection rate for combined invasive/micro-invasive and high-grade DCIS (IHG) detection rate and the low/intermediate grade DCIS (LIG) detection rate.</p> <p><strong>Results </strong>At prevalent screens for IHG cancers, 99% of the MMV was reached at a recall rate of 7.0%. The LIG detection rate had no discernible plateau, increasing linearly at a rate of 0.12 per 1000 for every 1% increase in recall rate. At incident screens, 99% of the MMV for IHG cancer detection was 4.0%. LIG DCIS increased linearly at a rate of 0.18 per 1000 per 1% increase in recall rate.</p> <p><strong>Conclusions </strong>Our models demonstrate the diminishing returns associated with increasing recall rates. The screening programme in England could use the models to set recall rate ranges, and other countries could explore similar methodology.</p> |
| first_indexed | 2024-03-06T20:39:59Z |
| format | Journal article |
| id | oxford-uuid:33f58ae9-c36f-426a-a36e-c562fd5da219 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:39:59Z |
| publishDate | 2019 |
| publisher | Springer |
| record_format | dspace |
| spelling | oxford-uuid:33f58ae9-c36f-426a-a36e-c562fd5da2192022-03-26T13:23:08ZAn analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programmeJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:33f58ae9-c36f-426a-a36e-c562fd5da219EnglishSymplectic Elements at OxfordSpringer2019Blanks, RGiven-Wilson, RCohen, SPatnick, JAlison, RWallis, M<p><strong>Objective </strong>To develop methods to model the relationship between cancer detection and recall rates to inform professional standards.</p> <p><strong>Methods </strong>Annual screening programme information for each of the 80 English NHSBSP units (totalling 11.3 million screening tests) for the seven screening years from 1 April 2009 to 31 March 2016 and some Dutch screening programme information were used to produce linear and non-linear models. The non-linear models estimated the modelled maximum values (MMV) for cancers detected at different grades and estimated how rapidly the MMV was reached (the modelled ‘slope’ (MS)). Main outcomes include the detection rate for combined invasive/micro-invasive and high-grade DCIS (IHG) detection rate and the low/intermediate grade DCIS (LIG) detection rate.</p> <p><strong>Results </strong>At prevalent screens for IHG cancers, 99% of the MMV was reached at a recall rate of 7.0%. The LIG detection rate had no discernible plateau, increasing linearly at a rate of 0.12 per 1000 for every 1% increase in recall rate. At incident screens, 99% of the MMV for IHG cancer detection was 4.0%. LIG DCIS increased linearly at a rate of 0.18 per 1000 per 1% increase in recall rate.</p> <p><strong>Conclusions </strong>Our models demonstrate the diminishing returns associated with increasing recall rates. The screening programme in England could use the models to set recall rate ranges, and other countries could explore similar methodology.</p> |
| spellingShingle | Blanks, R Given-Wilson, R Cohen, S Patnick, J Alison, R Wallis, M An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme |
| title | An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme |
| title_full | An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme |
| title_fullStr | An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme |
| title_full_unstemmed | An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme |
| title_short | An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme |
| title_sort | analysis of 11 3 million screening tests examining the association between recall and cancer detection rates in the english nhs breast cancer screening programme |
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