Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes.

Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes.

Trypanosoma brucei is a protozoan parasite that causes African sleeping sickness. T. brucei multiplies extracellularly in the bloodstream, relying on antigenic variation of a dense variant surface glycoprotein (VSG) coat to escape antibody-mediated lysis. We investigated the role of VSG in prolifera...

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Bibliographic Details
Main Authors:	Sheader, K, Vaughan, S, Minchin, J, Hughes, K, Gull, K, Rudenko, G
Format:	Journal article
Language:	English
Published:	2005

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