Dectin-1 is required for beta-glucan recognition and control of fungal infection.
Beta-glucan is one of the most abundant polysaccharides in fungal pathogens, yet its importance in antifungal immunity is unclear. Here we show that deficiency of dectin-1, the myeloid receptor for beta-glucan, rendered mice susceptible to infection with Candida albicans. Dectin-1-deficient leukocyt...
| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
2007
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