Dectin-1 is required for beta-glucan recognition and control of fungal infection.

Dectin-1 is required for beta-glucan recognition and control of fungal infection.

Beta-glucan is one of the most abundant polysaccharides in fungal pathogens, yet its importance in antifungal immunity is unclear. Here we show that deficiency of dectin-1, the myeloid receptor for beta-glucan, rendered mice susceptible to infection with Candida albicans. Dectin-1-deficient leukocyt...

Полное описание

Библиографические подробности
Главные авторы:	Taylor, P, Tsoni, S, Willment, J, Dennehy, K, Rosas, M, Findon, H, Haynes, K, Steele, C, Botto, M, Gordon, S, Brown, G
Формат:	Journal article
Язык:	English
Опубликовано:	2007

Схожие документы

Soluble Dectin-1 as a tool to detect beta-glucans.
по: Graham, L, и др.
Опубликовано: (2006)

Dectin-1 mediates the biological effects of beta-glucans.
по: Brown, G, и др.
Опубликовано: (2003)

Dectin-1 is a major beta-glucan receptor on macrophages.
по: Brown, G, и др.
Опубликовано: (2002)

Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function.
по: Brown, J, и др.
Опубликовано: (2007)

The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus.
по: Chad Steele, и др.
Опубликовано: (2005-12-01)

Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation.
по: Jacqueline U McDonald, и др.
Опубликовано: (2012-01-01)

Dectin-1 isoforms in mice are functionally different
по: Heinsbroek, SE, и др.
Опубликовано: (2005)

Characterisation of the human beta-glucan receptor
по: Willment, J, и др.
Опубликовано: (2005)

Prolonged reduction of leukocyte membrane-associated Dectin-1 levels following beta-glucan administration.
по: Ozment-Skelton, T, и др.
Опубликовано: (2006)

Expression of functionally different dectin-1 isoforms by murine macrophages.
по: Heinsbroek, SE, и др.
Опубликовано: (2006)

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.
по: Dennehy, K, и др.
Опубликовано: (2008)

Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions.
по: Reid, D, и др.
Опубликовано: (2004)

Immune recognition. A new receptor for beta-glucans.
по: Brown, G, и др.
Опубликовано: (2001)

Complement receptor 3, not Dectin-1, is the major receptor on human neutrophils for beta-glucan-bearing particles.
по: van Bruggen, R, и др.
Опубликовано: (2009)

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages
по: Esteban, Alexandre, и др.
Опубликовано: (2012)

The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose.
по: McGreal, E, и др.
Опубликовано: (2006)

Study the Toll-like Receptor 2 and Dectin-1 in mice treated with beta? glucans and infected with Salmonella Typhimurium
по: Nidhal R. Mahdi
Опубликовано: (2019-06-01)

The Role of Dectin-1-Akt-RNF146 Pathway in β-Glucan Induced Immune Trained State of Monocyte in Sepsis
по: Guo C, и др.
Опубликовано: (2025-01-01)

An Alpha-Glucan from <i>Lomentospora prolificans</i> Mediates Fungal–Host Interaction Signaling through Dectin-1 and Mincle
по: Mariana Ingrid Dutra da Silva Xisto, и др.
Опубликовано: (2023-02-01)

Characterisation of innate fungal recognition in the lung.
по: Inês Faro-Trindade, и др.
Опубликовано: (2012-01-01)

Leukocyte Dectin-1 expression is differentially regulated in fungal versus polymicrobial sepsis.
по: Ozment-Skelton, T, и др.
Опубликовано: (2009)

Systems Level Dissection of Candida Recognition by Dectins: A Matter of Fungal Morphology and Site of Infection
по: Lisa Rizzetto, и др.
Опубликовано: (2015-08-01)

Deletion of both Dectin-1 and Dectin-2 affects the bacterial but not fungal gut microbiota and susceptibility to colitis in mice
по: Yazhou Wang, и др.
Опубликовано: (2022-06-01)

Dectin-1 Is Required for Resistance to Coccidioidomycosis in Mice
по: Suganya Viriyakosol, и др.
Опубликовано: (2013-03-01)

Immune effects of β-glucan are determined by combined effects on Dectin-1, TLR2, 4 and 5
по: Pochanart Kanjan, и др.
Опубликовано: (2017-10-01)

Protection by anti-beta-glucan antibodies is associated with restricted beta-1,3 glucan binding specificity and inhibition of fungal growth and adherence.
по: Antonella Torosantucci, и др.
Опубликовано: (2009-01-01)

Dectin-1-Mediated Production of Pro-Inflammatory Cytokines Induced by Yeast β-Glucans in Bovine Monocytes
по: Ana R. V. Pedro, и др.
Опубликовано: (2021-05-01)

Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2.
по: Sonja I Gringhuis, и др.
Опубликовано: (2011-01-01)

β-Glucan induced plasma B cells differentiation to enhance antitumor immune responses by Dectin-1
по: Yu Bai, и др.
Опубликовано: (2025-01-01)

Dectin-3 Is Not Required for Protection against Cryptococcus neoformans Infection.
по: Althea Campuzano, и др.
Опубликовано: (2017-01-01)

Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side-chain branching.
по: Adams, E, и др.
Опубликовано: (2008)

Dectin-1
по: Herre, J, и др.
Опубликовано: (2004)

Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2
по: Shojiro Haji, и др.
Опубликовано: (2022-12-01)

Dectin-2 exhibits activation dependent expression on maturing inflammatory monocytes elicited in vivo
по: Taylor, P, и др.
Опубликовано: (2005)

Elevated level of beta-D-glucan in Pseudomonas infection
по: K. Shrestha, и др.
Опубликовано: (2024-01-01)

β-Glucan Size Controls Dectin-1-Mediated Immune Responses in Human Dendritic Cells by Regulating IL-1β Production
по: Matthew J. Elder, и др.
Опубликовано: (2017-07-01)

Viscosity of beta-glucan in oat products
по: H. ANTTILA, и др.
Опубликовано: (2008-12-01)

High-beta-glucan and low-glycemic index functional bulgur produced from high-beta-glucan barley
по: Zeynep Hazal Tekin-Cakmak, и др.
Опубликовано: (2024-01-01)

Development of an orange-flavoured functional beverage formulated with beta-glucan and coenzyme Q10-impregnated beta-glucan
по: Nian Liu, и др.
Опубликовано: (2018-08-01)

Recognition of yeast β-glucan particles triggers immunometabolic signaling required for trained immunity
по: Cian J.H. Horneck Johnston, и др.
Опубликовано: (2024-03-01)