RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI.

The trade-off between signal-to-noise ratio (SNR) and spatial specificity governs the choice of spatial resolution in magnetic resonance imaging (MRI); diffusion-weighted (DW) MRI is no exception. Images of lower resolution have higher signal to noise ratio, but also more partial volume artifacts. W...

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Main Authors: Sotiropoulos, SN, Jbabdi, S, Andersson, J, Woolrich, M, Ugurbil, K, Behrens, T
Format: Journal article
Language:English
Published: 2013
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author Sotiropoulos, SN
Jbabdi, S
Andersson, J
Woolrich, M
Ugurbil, K
Behrens, T
author_facet Sotiropoulos, SN
Jbabdi, S
Andersson, J
Woolrich, M
Ugurbil, K
Behrens, T
author_sort Sotiropoulos, SN
collection OXFORD
description The trade-off between signal-to-noise ratio (SNR) and spatial specificity governs the choice of spatial resolution in magnetic resonance imaging (MRI); diffusion-weighted (DW) MRI is no exception. Images of lower resolution have higher signal to noise ratio, but also more partial volume artifacts. We present a data-fusion approach for tackling this trade-off by combining DW MRI data acquired both at high and low spatial resolution. We combine all data into a single Bayesian model to estimate the underlying fiber patterns and diffusion parameters. The proposed model, therefore, combines the benefits of each acquisition. We show that fiber crossings at the highest spatial resolution can be inferred more robustly and accurately using such a model compared to a simpler model that operates only on high-resolution data, when both approaches are matched for acquisition time.
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spelling oxford-uuid:341aebac-f386-46c6-affe-81299f565a092022-03-26T13:24:06ZRubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:341aebac-f386-46c6-affe-81299f565a09EnglishSymplectic Elements at Oxford2013Sotiropoulos, SNJbabdi, SAndersson, JWoolrich, MUgurbil, KBehrens, TThe trade-off between signal-to-noise ratio (SNR) and spatial specificity governs the choice of spatial resolution in magnetic resonance imaging (MRI); diffusion-weighted (DW) MRI is no exception. Images of lower resolution have higher signal to noise ratio, but also more partial volume artifacts. We present a data-fusion approach for tackling this trade-off by combining DW MRI data acquired both at high and low spatial resolution. We combine all data into a single Bayesian model to estimate the underlying fiber patterns and diffusion parameters. The proposed model, therefore, combines the benefits of each acquisition. We show that fiber crossings at the highest spatial resolution can be inferred more robustly and accurately using such a model compared to a simpler model that operates only on high-resolution data, when both approaches are matched for acquisition time.
spellingShingle Sotiropoulos, SN
Jbabdi, S
Andersson, J
Woolrich, M
Ugurbil, K
Behrens, T
RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI.
title RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI.
title_full RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI.
title_fullStr RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI.
title_full_unstemmed RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI.
title_short RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI.
title_sort rubix combining spatial resolutions for bayesian inference of crossing fibers in diffusion mri
work_keys_str_mv AT sotiropoulossn rubixcombiningspatialresolutionsforbayesianinferenceofcrossingfibersindiffusionmri
AT jbabdis rubixcombiningspatialresolutionsforbayesianinferenceofcrossingfibersindiffusionmri
AT anderssonj rubixcombiningspatialresolutionsforbayesianinferenceofcrossingfibersindiffusionmri
AT woolrichm rubixcombiningspatialresolutionsforbayesianinferenceofcrossingfibersindiffusionmri
AT ugurbilk rubixcombiningspatialresolutionsforbayesianinferenceofcrossingfibersindiffusionmri
AT behrenst rubixcombiningspatialresolutionsforbayesianinferenceofcrossingfibersindiffusionmri