Modelling multiscale aspects of colorectal cancer
Colorectal cancer (CRC) is responsible for nearly half a million deaths annually world-wide [11]. We present a series of mathematical models describing the dynamics of the intestinal epithelium and the kinetics of the molecular pathway most commonly mutated in CRC, the Wnt signalling network. We als...
Main Authors: | Van Leeuwen, I, Byrne, H, Johnston, MD, Edwards, C, Chapman, S, Bodmer, W, Maini, P |
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Format: | Journal article |
Language: | English |
Published: |
2007
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