Inward rectification in KATP channels: a pH switch in the pore.

Inward-rectifier potassium channels (Kir channels) stabilize the resting membrane potential and set a threshold for excitation in many types of cell. This function arises from voltage-dependent rectification of these channels due to blockage by intracellular polyamines. In all Kir channels studied t...

Descripción completa

Detalles Bibliográficos
Autores principales: Baukrowitz, T, Tucker, S, Schulte, U, Benndorf, K, Ruppersberg, J, Fakler, B
Formato: Journal article
Lenguaje:English
Publicado: 1999