Inward rectification in KATP channels: a pH switch in the pore.
Inward-rectifier potassium channels (Kir channels) stabilize the resting membrane potential and set a threshold for excitation in many types of cell. This function arises from voltage-dependent rectification of these channels due to blockage by intracellular polyamines. In all Kir channels studied t...
Main Authors: | Baukrowitz, T, Tucker, S, Schulte, U, Benndorf, K, Ruppersberg, J, Fakler, B |
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Format: | Journal article |
Language: | English |
Published: |
1999
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