Spatial working memory deficits in GluA1 AMPA receptor subunit knockout mice reflect impaired short-term habituation: evidence for Wagner's dual-process memory model.

Genetically modified mice, lacking the GluA1 AMPA receptor subunit, are impaired on spatial working memory tasks, but display normal acquisition of spatial reference memory tasks. One explanation for this dissociation is that working memory, win-shift performance engages a GluA1-dependent, non-assoc...

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Main Authors: Sanderson, D, McHugh, S, Good, M, Sprengel, R, Seeburg, P, Rawlins, J, Bannerman, D
格式: Journal article
语言:English
出版: 2010