Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines.

Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines.

BACKGROUND: BNIP3 is a hypoxia-induced protein involved in cell death and survival but its role in human tumors is unclear. This study investigated the role of BNIP3 in prostate cancer. METHODS: The expression of BNIP3, the androgen receptor (AR), hypoxia inducible factor (HIF)-1alpha, HIF-2alpha a...

Podrobná bibliografie
Hlavní autoři:	Shaida, N, Launchbury, R, Boddy, J, Jones, C, Campo, L, Turley, H, Kanga, S, Banham, A, Malone, P, Harris, A, Fox, S
Médium:	Journal article
Jazyk:	English
Vydáno:	2008

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