5,6-Dihydrothymine impairs the base excision repair pathway of a closely opposed AP site or single-strand break.

5,6-Dihydrothymine impairs the base excision repair pathway of a closely opposed AP site or single-strand break.

Ionizing radiation can induce clustered DNA damage (two or more lesions formed within one to two helical turns of DNA by passage of a single ionization track). Using oligonucleotide constructs containing clustered DNA lesions at defined positions, evidence is presented demonstrating that a persisten...

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Dettagli Bibliografici
Autori principali:	Byrne, S, Cunniffe, S, O'Neill, P, Lomax, M
Natura:	Journal article
Lingua:	English
Pubblicazione:	2009

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