5,6-Dihydrothymine impairs the base excision repair pathway of a closely opposed AP site or single-strand break.

Ionizing radiation can induce clustered DNA damage (two or more lesions formed within one to two helical turns of DNA by passage of a single ionization track). Using oligonucleotide constructs containing clustered DNA lesions at defined positions, evidence is presented demonstrating that a persisten...

Полное описание

Библиографические подробности
Главные авторы: Byrne, S, Cunniffe, S, O'Neill, P, Lomax, M
Формат: Journal article
Язык:English
Опубликовано: 2009