Co-proxamol and suicide: a study of national mortality statistics and local non-fatal self poisonings.
OBJECTIVES: To examine the incidence of suicides due to co-proxamol compared with tricyclic antidepressants and paracetamol, and to compare fatality rates for self poisonings with these drugs. DESIGN: Analysis of routinely collected national and local data on suicides and self poisonings. SETTING:...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2003
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| _version_ | 1797062170074152960 |
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| author | Hawton, K Simkin, S Deeks, J |
| author_facet | Hawton, K Simkin, S Deeks, J |
| author_sort | Hawton, K |
| collection | OXFORD |
| description | OBJECTIVES: To examine the incidence of suicides due to co-proxamol compared with tricyclic antidepressants and paracetamol, and to compare fatality rates for self poisonings with these drugs. DESIGN: Analysis of routinely collected national and local data on suicides and self poisonings. SETTING: Records of suicides in England and Wales 1997-9; non-fatal self poisonings in Oxford District 1997-9. DATA SOURCES: Office for National Statistics and Oxford monitoring system for attempted suicide. MAIN OUTCOME MEASURES: Incidence of suicides with co-proxamol or tricyclic antidepressants or paracetamol. Ratios of fatal to non-fatal self poisonings. RESULTS: Co-proxamol alone accounted for 5% of all suicides. Of 4162 drug related suicides, 18% (766) involved co-proxamol alone, 22% (927) tricyclic antidepressants alone, and 9% (368) paracetamol alone. A higher proportion of suicides in the 10-24 year age group were due to co-proxamol than in the other age groups. The odds of dying after overdose with co-proxamol was 2.3 times (95% confidence interval 2.1 to 2.5) that for tricyclic antidepressants and 28.1 times (24.9 to 32.9) that for paracetamol. CONCLUSIONS: Self poisoning with co-proxamol is particularly dangerous and contributes substantially to drug related suicides. Restricting availability of co-proxamol could have an important role in suicide prevention. |
| first_indexed | 2024-03-06T20:41:45Z |
| format | Journal article |
| id | oxford-uuid:3486c7a9-ed1b-4660-a560-d55ddb1c3c88 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:41:45Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | oxford-uuid:3486c7a9-ed1b-4660-a560-d55ddb1c3c882022-03-26T13:26:25ZCo-proxamol and suicide: a study of national mortality statistics and local non-fatal self poisonings.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3486c7a9-ed1b-4660-a560-d55ddb1c3c88EnglishSymplectic Elements at Oxford2003Hawton, KSimkin, SDeeks, J OBJECTIVES: To examine the incidence of suicides due to co-proxamol compared with tricyclic antidepressants and paracetamol, and to compare fatality rates for self poisonings with these drugs. DESIGN: Analysis of routinely collected national and local data on suicides and self poisonings. SETTING: Records of suicides in England and Wales 1997-9; non-fatal self poisonings in Oxford District 1997-9. DATA SOURCES: Office for National Statistics and Oxford monitoring system for attempted suicide. MAIN OUTCOME MEASURES: Incidence of suicides with co-proxamol or tricyclic antidepressants or paracetamol. Ratios of fatal to non-fatal self poisonings. RESULTS: Co-proxamol alone accounted for 5% of all suicides. Of 4162 drug related suicides, 18% (766) involved co-proxamol alone, 22% (927) tricyclic antidepressants alone, and 9% (368) paracetamol alone. A higher proportion of suicides in the 10-24 year age group were due to co-proxamol than in the other age groups. The odds of dying after overdose with co-proxamol was 2.3 times (95% confidence interval 2.1 to 2.5) that for tricyclic antidepressants and 28.1 times (24.9 to 32.9) that for paracetamol. CONCLUSIONS: Self poisoning with co-proxamol is particularly dangerous and contributes substantially to drug related suicides. Restricting availability of co-proxamol could have an important role in suicide prevention. |
| spellingShingle | Hawton, K Simkin, S Deeks, J Co-proxamol and suicide: a study of national mortality statistics and local non-fatal self poisonings. |
| title | Co-proxamol and suicide: a study of national mortality statistics and local non-fatal self poisonings. |
| title_full | Co-proxamol and suicide: a study of national mortality statistics and local non-fatal self poisonings. |
| title_fullStr | Co-proxamol and suicide: a study of national mortality statistics and local non-fatal self poisonings. |
| title_full_unstemmed | Co-proxamol and suicide: a study of national mortality statistics and local non-fatal self poisonings. |
| title_short | Co-proxamol and suicide: a study of national mortality statistics and local non-fatal self poisonings. |
| title_sort | co proxamol and suicide a study of national mortality statistics and local non fatal self poisonings |
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