c-erbB-2 related aggressiveness in breast cancer is hypoxia inducible factor-1alpha dependent.

c-erbB-2 related aggressiveness in breast cancer is hypoxia inducible factor-1alpha dependent.

c-erbB-2-positive breast carcinomas are highly aggressive tumors. In vitro data on breast cell lines showed that c-erbB-2 enhanced translational efficiency of hypoxia inducible factor-1alpha (HIF1alpha) production (Laughner et al., Mol Cell Biol 2001;21:3995-4005). We investigated the clinical corre...

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Bibliographic Details
Main Authors:	Giatromanolaki, A, Koukourakis, M, Simopoulos, C, Polychronidis, A, Gatter, K, Harris, A, Sivridis, E
Format:	Journal article
Language:	English
Published:	2004

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