The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin.

BACKGROUND: alpha-Momorcharin (alpha MMC) is a type I ribosome-inactivating protein. It inhibits protein synthesis by hydrolytically removing a specific adenine residue from a highly conserved, single-stranded loop of rRNA. RESULTS: Here we describe the determination and refinement of the crystal st...

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Bibliografische gegevens
Hoofdauteurs: Ren, J, Wang, Y, Dong, Y, Stuart, D
Formaat: Journal article
Taal:English
Gepubliceerd in: 1994