Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process.
Tag team: The flouro-detagging of flourous sulfonates by the [ 18F]fluoride ion was found to be an advantageous strategy for the preparation of various 18F-labeled prosthetic groups and known radiotracers (see picture). Fluorous solid phase extraction (FSPE) was used to separate the excess fluorous...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2009
|
| _version_ | 1797062216578498560 |
|---|---|
| author | Bejot, R Fowler, T Carroll, L Boldon, S Moore, J Declerck, J Gouverneur, V |
| author_facet | Bejot, R Fowler, T Carroll, L Boldon, S Moore, J Declerck, J Gouverneur, V |
| author_sort | Bejot, R |
| collection | OXFORD |
| description | Tag team: The flouro-detagging of flourous sulfonates by the [ 18F]fluoride ion was found to be an advantageous strategy for the preparation of various 18F-labeled prosthetic groups and known radiotracers (see picture). Fluorous solid phase extraction (FSPE) was used to separate the excess fluorous precursor from the labeled material, which suggests that traditional purification protocols such as distillation or tedious separation can be avoided. (Chemical Equation Presented). © 2009 Wiley-VCH Verlag GmbH and Co. KGaA. |
| first_indexed | 2024-03-06T20:42:21Z |
| format | Journal article |
| id | oxford-uuid:34b2edb4-f26d-43dc-9de4-cca16a32f0eb |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:42:21Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:34b2edb4-f26d-43dc-9de4-cca16a32f0eb2022-03-26T13:27:33ZFluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:34b2edb4-f26d-43dc-9de4-cca16a32f0ebEnglishSymplectic Elements at Oxford2009Bejot, RFowler, TCarroll, LBoldon, SMoore, JDeclerck, JGouverneur, VTag team: The flouro-detagging of flourous sulfonates by the [ 18F]fluoride ion was found to be an advantageous strategy for the preparation of various 18F-labeled prosthetic groups and known radiotracers (see picture). Fluorous solid phase extraction (FSPE) was used to separate the excess fluorous precursor from the labeled material, which suggests that traditional purification protocols such as distillation or tedious separation can be avoided. (Chemical Equation Presented). © 2009 Wiley-VCH Verlag GmbH and Co. KGaA. |
| spellingShingle | Bejot, R Fowler, T Carroll, L Boldon, S Moore, J Declerck, J Gouverneur, V Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process. |
| title | Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process. |
| title_full | Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process. |
| title_fullStr | Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process. |
| title_full_unstemmed | Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process. |
| title_short | Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process. |
| title_sort | fluorous synthesis of 18f radiotracers with the 18f fluoride ion nucleophilic fluorination as the detagging process |
| work_keys_str_mv | AT bejotr fluoroussynthesisof18fradiotracerswiththe18ffluorideionnucleophilicfluorinationasthedetaggingprocess AT fowlert fluoroussynthesisof18fradiotracerswiththe18ffluorideionnucleophilicfluorinationasthedetaggingprocess AT carrolll fluoroussynthesisof18fradiotracerswiththe18ffluorideionnucleophilicfluorinationasthedetaggingprocess AT boldons fluoroussynthesisof18fradiotracerswiththe18ffluorideionnucleophilicfluorinationasthedetaggingprocess AT moorej fluoroussynthesisof18fradiotracerswiththe18ffluorideionnucleophilicfluorinationasthedetaggingprocess AT declerckj fluoroussynthesisof18fradiotracerswiththe18ffluorideionnucleophilicfluorinationasthedetaggingprocess AT gouverneurv fluoroussynthesisof18fradiotracerswiththe18ffluorideionnucleophilicfluorinationasthedetaggingprocess |