Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP

Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP

<p>Heterologous prime-boost vaccination with viral vectors simian adenovirus 63 (ChAd63) and Modified Vaccinia Ankara (MVA) induces potent T cell and antibody responses in humans. The 8-week regimen demonstrates significant efficacy against malaria when expressing the pre-erythrocytic malaria...

书目详细资料
Main Authors:	Bliss, C, Bowyer, G, Anagnostou, N, Havelock, T, Snudden, C, Davies, H, de Cassan, S, Grobbelaar, A, Lawrie, A, Venkatraman, N, Poulton, I, Roberts, R, Mange, P, Choudhary, P, Faust, S, Colloca, S, Gilbert, S, Nicosia, A, Hill, A, Ewer, K
格式:	Journal article
出版:	Springer Nature 2018

相似书籍

Safety and high level efficacy of the combination malaria vaccine regimen of RTS,S/AS01B with ChAd-MVA vectored vaccines expressing ME-TRAP
由: Rampling, T, et al.
出版: (2016)

Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals.
由: Hodgson, S, et al.
出版: (2014)

Evaluation of the efficacy of chad63-mva vectored vaccines expressing circumsporozoite protein and me-trap against controlled human malaria infection in malaria-naive individuals
由: Hodgson, SH, et al.
出版: (2014)

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP
由: Rampling, T, et al.
出版: (2016)

Safety and Efficacy of Novel Malaria Vaccine Regimens of RTS,S/AS01B alone, or with Concomitant ChAd63-MVA Vectored Vaccines Expressing ME-TRAP
由: Rampling, T, et al.
出版: (2018)

ChAd63-MVA-vectored blood-stage Malaria vaccines targeting MSP1 and AMA1: Assessment of efficacy against mosquito bite challenge in humans
由: Sheehy, S, et al.
出版: (2012)

Safety and immunogenicity of heterologous prime-boost immunization with viral-vectored malaria vaccines adjuvanted with Matrix-M
由: Venkatraman, N, et al.
出版: (2017)

Safety and immunogenicity of the heterologous prime-boost ebolavirus vaccine regimen CHAD3-EBO Z and MVA-BN (R) FILO in healthy UK adults
由: Rampling, T, et al.
出版: (2015)

CXCR3+ T follicular helper cells induced by co-administration of RTS,S/AS01B and viral vectored vaccines are associated with reduced immunogenicity and efficacy against Malaria
由: Ewer (nee Russell), K, et al.
出版: (2018)

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults.
由: Ogwang, C, et al.
出版: (2013)

Prime-boost vectored malaria vaccines: progress and prospects.
由: Hill, A, et al.
出版: (2010)

ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans.
由: Sheehy, S, et al.
出版: (2012)

Safety and immunogenicity of malaria vectored vaccines given with routine EPI vaccines in Gambian infants and neonates: a randomized controlled trial
由: Mensah, V, et al.
出版: (2017)

First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children
由: Tiono, AB, et al.
出版: (2018)

NEUTRALIZING ANTIBODY TITERS TO SIMIAN ADENOVIRAL VECTORS FOLLOWING ADCH63 ME-TRAP IMMUNIZATION IN HUMANS
由: Goodman, A, et al.
出版: (2009)

Viral vector malaria vaccines induce high-level T cell and antibody responses in West African children and infants
由: Bliss, C, et al.
出版: (2016)

Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African children and infants
由: Bliss, C, et al.
出版: (2016)

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.
由: Mensah, V, et al.
出版: (2016)

Viral vectored blood-stage malaria vaccines induce B cell responses in humans that can be boosted by controlled malaria infection
由: Elias, S, et al.
出版: (2014)

Expansion of CD57+KLRG1+ T cells is associated with reduced vaccine responses in CMV+ young adults
由: Bowyer, G, et al.
出版: (2020)

Safety and immunogenicity of a heterologous prime-boost Ebola virus vaccine regimen in healthy adults in the United Kingdom and Senegal
由: Venkatraman, N, et al.
出版: (2018)

A review of Phase I trials of Ebolavirus vaccines: What can we learn from the race to develop novel vaccines?
由: Lambe, T, et al.
出版: (2017)

A monovalent chimpanzee adenovirus Ebola vaccine — preliminary report
由: Rampling, T, et al.
出版: (2015)

Detection of vaccine-induced antibodies to Ebola virus in oral fluid
由: Lambe, T, et al.
出版: (2016)

A three-antigen Plasmodium falciparum DNA prime—Adenovirus boost malaria vaccine regimen is superior to a two-antigen regimen and protects against controlled human malaria infection in healthy malaria-naïve adults
由: Sklar, MJ, et al.
出版: (2021)

A Phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS
由: De Barra, E, et al.
出版: (2014)

HETEROLOGOUS PRIME-BOOST VACCINATION WITH ADCH63 AND MVA EXPRESSING MSP1 CAN INDUCE PROTECTIVE EFFICACY AGAINST SPOROZOITE CHALLENGE IN VOLUNTEERS
由: Sheehy, S, et al.
出版: (2010)

Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain.
由: Spencer, A, et al.
出版: (2014)

Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine
由: Folegatti, P, et al.
出版: (2019)

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults.
由: Caroline Ogwang, et al.
出版: (2013-01-01)

Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector.
由: O'Hara, G, et al.
出版: (2012)

Phase Ia clinical evaluation of the plasmodium falciparum blood-stage antigen MSP1 in ChAd63 and MVA vaccine vectors
由: Sheehy, S, et al.
出版: (2011)

Phase Ia clinical evaluation of the Plasmodium falciparum blood-stage antigen MSP1 in ChAd63 and MVA vaccine vectors.
由: Sheehy, S, et al.
出版: (2011)

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.
由: Victorine A Mensah, et al.
出版: (2016-01-01)

Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species.
由: Colloca, S, et al.
出版: (2012)

A monovalent chimpanzee adenovirus ebola vaccine boosted with MVA
由: Ewer (nee Russell), K, et al.
出版: (2016)

Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial.
由: Hodgson, S, et al.
出版: (2014)

First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children.
由: Alfred B Tiono, et al.
出版: (2018-01-01)

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors.
由: Sheehy, S, et al.
出版: (2012)

CLINICAL EVALUATION OF NEW VIRAL VECTORED VACCINES TARGETING THE PLASMODIUM FALCIPARUM BLOOD-STAGE ANTIGENS; MSP1 AND AMA1
由: Sheehy, S, et al.
出版: (2011)