Radiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy.
In proton therapy, a radiobiological effectiveness ratio (RBE) of 1.1 (RBE1.1) is often used. In reality, RBE depends on dose, linear energy transfer (LET), biological end point, and tissue type. Using a value of RBE that may be not accurate may affect dose calculation and hence, outcome.
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Elsevier
2016
|
_version_ | 1826266726498566144 |
---|---|
author | Madkhali, A Timlin, C Partridge, M |
author_facet | Madkhali, A Timlin, C Partridge, M |
author_sort | Madkhali, A |
collection | OXFORD |
description | In proton therapy, a radiobiological effectiveness ratio (RBE) of 1.1 (RBE1.1) is often used. In reality, RBE depends on dose, linear energy transfer (LET), biological end point, and tissue type. Using a value of RBE that may be not accurate may affect dose calculation and hence, outcome. |
first_indexed | 2024-03-06T20:43:21Z |
format | Journal article |
id | oxford-uuid:34fdfb91-8cf7-493a-89b5-9b59fb12e2bd |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T20:43:21Z |
publishDate | 2016 |
publisher | Elsevier |
record_format | dspace |
spelling | oxford-uuid:34fdfb91-8cf7-493a-89b5-9b59fb12e2bd2022-03-26T13:29:30ZRadiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:34fdfb91-8cf7-493a-89b5-9b59fb12e2bdEnglishSymplectic Elements at OxfordElsevier2016Madkhali, ATimlin, CPartridge, MIn proton therapy, a radiobiological effectiveness ratio (RBE) of 1.1 (RBE1.1) is often used. In reality, RBE depends on dose, linear energy transfer (LET), biological end point, and tissue type. Using a value of RBE that may be not accurate may affect dose calculation and hence, outcome. |
spellingShingle | Madkhali, A Timlin, C Partridge, M Radiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy. |
title | Radiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy. |
title_full | Radiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy. |
title_fullStr | Radiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy. |
title_full_unstemmed | Radiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy. |
title_short | Radiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy. |
title_sort | radiobiological effectiveness and its role in modeling secondary cancer risk for proton therapy |
work_keys_str_mv | AT madkhalia radiobiologicaleffectivenessanditsroleinmodelingsecondarycancerriskforprotontherapy AT timlinc radiobiologicaleffectivenessanditsroleinmodelingsecondarycancerriskforprotontherapy AT partridgem radiobiologicaleffectivenessanditsroleinmodelingsecondarycancerriskforprotontherapy |