Histone deacetylase inhibitors as radiosensitisers: Effects on DNA damage signalling and repair
Many cancers display increased expression of histone deacetylases (HDACs) and therefore transcriptionally inactive chromatin, resulting in the downregulation of genes including tumour suppressor and DNA repair genes. Histone deacetylase inhibitors (HDACi) are a heterogeneous group of epigenetic ther...
| Үндсэн зохиолчид: | , , , , |
|---|---|
| Формат: | Journal article |
| Хэл сонгох: | English |
| Хэвлэсэн: |
2013
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Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair.
Хэвлэсэн 2013
Journal article