Igh-6(-/-) (B-cell-deficient) mice fail to mount solid acquired resistance to oral challenge with virulent Salmonella enterica serovar typhimurium and show impaired Th1 T-cell responses to Salmonella antigens

Igh-6(-/-) (B-cell-deficient) mice fail to mount solid acquired resistance to oral challenge with virulent Salmonella enterica serovar typhimurium and show impaired Th1 T-cell responses to Salmonella antigens

Taispeáin leaganacha eile (1)

In the present study we evaluated the role of B cells in acquired immunity to Salmonella infection by using gene-targeted B-cell-deficient innately susceptible mice on a C57BL/6 background (Igh-6(-/-)). Igh-6(-/-) mice immunized with a live, attenuated aroA Salmonella enterica serovar Typhimurium va...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Mastroeni, P, Simmons, C, Fowler, R, al., E
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	American Society for Microbiology 2000

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