Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis.
BACKGROUND: Patients with diabetes mellitus are more prone to bacterial sepsis, but there are conflicting data on whether outcomes are worse in diabetics after presentation with sepsis. Glyburide is an oral hypoglycemic agent used to treat diabetes mellitus. This K(ATP)-channel blocker and broad-spe...
Auteurs principaux: | Koh, G, Maude, R, Schreiber, M, Limmathurotsakul, D, Wiersinga, W, Wuthiekanun, V, Lee, S, Mahavanakul, W, Chaowagul, W, Chierakul, W, White, N, van der Poll, T, Day, N, Dougan, G, Peacock, S |
---|---|
Format: | Journal article |
Langue: | English |
Publié: |
2011
|
Documents similaires
-
Risk factors for recurrent melioidosis in northeast Thailand.
par: Limmathurotsakul, D, et autres
Publié: (2006) -
Glyburide reduces bacterial dissemination in a mouse model of melioidosis.
par: Gavin C K W Koh, et autres
Publié: (2013-01-01) -
Role and significance of quantitative urine cultures in diagnosis of melioidosis.
par: Limmathurotsakul, D, et autres
Publié: (2005) -
Diabetes does not influence activation of coagulation, fibrinolysis or anticoagulant pathways in Gram-negative sepsis (melioidosis).
par: Koh, G, et autres
Publié: (2011) -
Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei.
par: Wiersinga, W, et autres
Publié: (2006)