Transmitting the message: intracellular mRNA localization.
The intracellular localization of mRNA is an important mechanism for targeting proteins to their sites of function. Localized transcripts play key roles ranging from body axis determination to synapse plasticity, and recent studies highlight how common localized transcripts are in a variety of model...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2010
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| _version_ | 1797062340203511808 |
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| author | Meignin, C Davis, I |
| author_facet | Meignin, C Davis, I |
| author_sort | Meignin, C |
| collection | OXFORD |
| description | The intracellular localization of mRNA is an important mechanism for targeting proteins to their sites of function. Localized transcripts play key roles ranging from body axis determination to synapse plasticity, and recent studies highlight how common localized transcripts are in a variety of model organisms. In this review, we consider the full range of known mechanisms for delivering transcripts and anchoring them at their site of function. Finally, we evaluate the progress that has been made in the nervous system in understanding the mechanism and function of mRNA localization and translation regulation. |
| first_indexed | 2024-03-06T20:44:08Z |
| format | Journal article |
| id | oxford-uuid:354ac31d-339a-4074-8866-44e882d1bcb0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:44:08Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:354ac31d-339a-4074-8866-44e882d1bcb02022-03-26T13:31:07ZTransmitting the message: intracellular mRNA localization.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:354ac31d-339a-4074-8866-44e882d1bcb0EnglishSymplectic Elements at Oxford2010Meignin, CDavis, IThe intracellular localization of mRNA is an important mechanism for targeting proteins to their sites of function. Localized transcripts play key roles ranging from body axis determination to synapse plasticity, and recent studies highlight how common localized transcripts are in a variety of model organisms. In this review, we consider the full range of known mechanisms for delivering transcripts and anchoring them at their site of function. Finally, we evaluate the progress that has been made in the nervous system in understanding the mechanism and function of mRNA localization and translation regulation. |
| spellingShingle | Meignin, C Davis, I Transmitting the message: intracellular mRNA localization. |
| title | Transmitting the message: intracellular mRNA localization. |
| title_full | Transmitting the message: intracellular mRNA localization. |
| title_fullStr | Transmitting the message: intracellular mRNA localization. |
| title_full_unstemmed | Transmitting the message: intracellular mRNA localization. |
| title_short | Transmitting the message: intracellular mRNA localization. |
| title_sort | transmitting the message intracellular mrna localization |
| work_keys_str_mv | AT meigninc transmittingthemessageintracellularmrnalocalization AT davisi transmittingthemessageintracellularmrnalocalization |