Caveolin-1 and -2 and their relationship to cerebral amyloid angiopathy in Alzheimer's disease.

Caveolin-1 and -2 and their relationship to cerebral amyloid angiopathy in Alzheimer's disease.

Cerebral amyloid angiopathy (CAA) affects over 90% of patients with Alzheimer's disease (AD) and increases the risk of cerebral haemorrhage and infarction. Caveolae--cholesterol-enriched plasmalemmal microinvaginations--are implicated in the production of amyloid beta peptide (Abeta). Caveolin-...

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Hlavní autoři: van Helmond, Z, Miners, J, Bednall, E, Chalmers, K, Zhang, Y, Wilcock, G, Love, S, Kehoe, P
Médium: Journal article
Jazyk:English
Vydáno: 2007

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