The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries
Triglyceride-rich lipoproteins (TRLs) undergo lipolysis by lipoprotein lipase (LPL), an enzyme that is transported to the capillary lumen by an endothelial cell protein, GPIHBP1. For LPL-mediated lipolysis to occur, TRLs must bind to the lumen of capillaries. This process is often assumed to involve...
Main Authors: | Goulbourne, C, Gin, P, Tatar, A, Nobumori, C, Hoenger, A, Jiang, H, Grovenor, C, Adeyo, O, Esko, J, Goldberg, I, Reue, K, Tontonoz, P, Bensadoun, A, Beigneux, A, Young, S, Fong, L |
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Format: | Journal article |
Language: | English |
Published: |
Cell Press
2014
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