The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

Membranes in cells have defined distributions of lipids in each leaflet, controlled by lipid scramblases and flip/floppases. However, for some intracellular membranes such as the endoplasmic reticulum (ER) the scramblases have not been identified. Members of the TMEM16 family have either lipid scram...

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Bibliographic Details
Main Authors: Bushell, SR, Pike, ACW, Falzone, ME, Rorsman, NJG, Ta, CM, Corey, RA, Newport, TD, Christianson, JC, Scofano, LF, Shintre, CA, Tessitore, A, Chu, A, Wang, Q, Shrestha, L, Mukhopadhyay, SMM, Love, JD, Burgess-Brown, NA, Sitsapesan, R, Stansfeld, PJ, Huiskonen, JT, Tammaro, P, Accardi, A, Carpenter, EP
Format: Journal article
Language:English
Published: Springer Nature 2019