A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.
Genetic susceptibility to multiple sclerosis is associated with genes of the major histocompatibility complex (MHC), particularly HLA-DRB1 and HLA-DQB1 (ref. 1). Both locus and allelic heterogeneity have been reported in this genomic region. To clarify whether HLA-DRB1 itself, nearby genes in the re...
المؤلفون الرئيسيون: | Lincoln, MR, Montpetit, A, Cader, M, Saarela, J, Dyment, D, Tiislar, M, Ferretti, V, Tienari, P, Sadovnick, A, Peltonen, L, Ebers, G, Hudson, T |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2005
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مواد مشابهة
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HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility.
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Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance.
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Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.
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Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium.
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Expression of the multiple sclerosis associated MHC class II allele HLA-DRBI*1501 is regulated by vitamin D
حسب: Ebers, G, وآخرون
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