A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.

Genetic susceptibility to multiple sclerosis is associated with genes of the major histocompatibility complex (MHC), particularly HLA-DRB1 and HLA-DQB1 (ref. 1). Both locus and allelic heterogeneity have been reported in this genomic region. To clarify whether HLA-DRB1 itself, nearby genes in the re...

Descripció completa

Dades bibliogràfiques
Autors principals:	Lincoln, MR, Montpetit, A, Cader, M, Saarela, J, Dyment, D, Tiislar, M, Ferretti, V, Tienari, P, Sadovnick, A, Peltonen, L, Ebers, G, Hudson, T
Format:	Journal article
Idioma:	English
Publicat:	2005

Ítems similars

HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility.
per: Chao, M, et al.
Publicat: (2008)

Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance.
per: Dyment, D, et al.
Publicat: (2005)

Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.
per: Ramagopalan, S, et al.
Publicat: (2009)

Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium.
per: Chao, M, et al.
Publicat: (2007)

Expression of the multiple sclerosis associated MHC class II allele HLA-DRBI*1501 is regulated by vitamin D
per: Ebers, G, et al.
Publicat: (2008)

Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium
per: Chao, M, et al.
Publicat: (2007)

Re: HLA-DRB1 and multiple sclerosis in Malta.
per: Ramagopalan, S, et al.
Publicat: (2008)

Follow-up investigation of 12 proposed linkage regions in multiple sclerosis.
per: Herrera, B, et al.
Publicat: (2006)

Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility.
per: Lincoln, MR, et al.
Publicat: (2009)

Expression of the multiple sclerosis associated MHC class II allele HLA-DRB1*1501 is regulated by vitamin D
per: Ebers, G, et al.
Publicat: (2008)

Epistasis among HLA-DRB1, HLA-DQA1 and HLA-DQB1 Loci Determines Multiple Sclerosis Susceptibility
per: Lincoln, MR, et al.
Publicat: (2009)

Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.
per: Sreeram V Ramagopalan, et al.
Publicat: (2009-02-01)

Maternal - offspring HLA-DRB1 compatibility in multiple sclerosis.
per: Willer, C, et al.
Publicat: (2005)

PRKCA and multiple sclerosis: Association in independent populations
per: Saarela, J, et al.
Publicat: (2006)

PRKCA and multiple sclerosis: association in two independent populations
per: Saarela, J, et al.
Publicat: (2006)

An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus.
per: DeLuca, G, et al.
Publicat: (2007)

Parental transmission of HLA-DRB1*15 in multiple sclerosis.
per: Ramagopalan, S, et al.
Publicat: (2008)

The MHC and multiple sclerosis susceptibility - several levels of complexity
per: Ebers, G, et al.
Publicat: (2004)

MHC transmission: insights into gender bias in MS susceptibility.
per: Chao, M, et al.
Publicat: (2011)

HLA-DRB1*15, low infant sibling exposure, and multiple sclerosis gene-environment interaction.
per: Ramagopalan, S, et al.
Publicat: (2010)

Parental non-inherited HLA resistance alleles do not confer protection against multiple sclerosis.
per: Ramagopalan, S, et al.
Publicat: (2008)

Confirmation of linkage between the HLA-DR locus and multiple sclerosis in two unusually large MS families.
per: Willer, C, et al.
Publicat: (1999)

A multigenerational family with multiple sclerosis.
per: Dyment, D, et al.
Publicat: (2002)

Exome sequencing identifies a novel multiple sclerosis susceptibility variant in the TYK2 gene.
per: Dyment, D, et al.
Publicat: (2012)

Genetics of multiple sclerosis.
per: Dyment, D, et al.
Publicat: (2004)

Genetic epidemiology of multiple sclerosis.
per: Sadovnick, A, et al.
Publicat: (1997)

RARE VARIANTS IN THE CYP27B1 GENE ARE ASSOCIATED WITH MULTIPLE SCLEROSIS
per: Ebers, G, et al.
Publicat: (2012)

PRKCA and multiple sclerosis: association in two independent populations.
per: Janna Saarela, et al.
Publicat: (2006-03-01)

Multiple sclerosis susceptibility and the X chromosome.
per: Herrera, B, et al.
Publicat: (2007)

Gestational diabetes and multiple sclerosis.
per: Ramagopalan, S, et al.
Publicat: (2009)

Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis
per: Ramagopalan, S, et al.
Publicat: (2008)

Parent-of-origin of HLA-DRB1*1501 and age of onset of multiple sclerosis.
per: Ramagopalan, S, et al.
Publicat: (2009)

Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex.
per: Chao, M, et al.
Publicat: (2009)

Genetics of multiple sclerosis (vol 6, pg 1693, 1997)
per: Dyment, D, et al.
Publicat: (1997)

Genetics of multiple sclerosis.
per: Dyment, D, et al.
Publicat: (1997)

Effects of infectious mononucleosis and HLA-DRB1*15 in multiple sclerosis.
per: Ramagopalan, S, et al.
Publicat: (2010)

An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1gene
per: Ramagopalan, S, et al.
Publicat: (2009)

Erratum: Genetics of multiple sclerosis (Human Molecular Genetics (1997) 6 (1693-1698))
per: Dyment, D, et al.
Publicat: (1997)

HLA B*44: protective effects in MS susceptibility and MRI outcome measures.
per: Chao, M, et al.
Publicat: (2011)

IS THERE A MATERNAL EFFECT IN MULTIPLE-SCLEROSIS
per: Dyment, D, et al.
Publicat: (1995)