A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.

Genetic susceptibility to multiple sclerosis is associated with genes of the major histocompatibility complex (MHC), particularly HLA-DRB1 and HLA-DQB1 (ref. 1). Both locus and allelic heterogeneity have been reported in this genomic region. To clarify whether HLA-DRB1 itself, nearby genes in the re...

書誌詳細
主要な著者:	Lincoln, MR, Montpetit, A, Cader, M, Saarela, J, Dyment, D, Tiislar, M, Ferretti, V, Tienari, P, Sadovnick, A, Peltonen, L, Ebers, G, Hudson, T
フォーマット:	Journal article
言語:	English
出版事項:	2005

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