MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex.

MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex.

MeCP2 is a transcription factor that recognizes and binds symmetrically methylated CpG dinucleotides to repress transcription. MeCP2 can associate with the Sin3a/histone deacetylase corepressor complex and mediate repression in a histone deacetylase-dependent manner. In extracts from rodent tissues,...

Полное описание

Библиографические подробности
Главные авторы:	Klose, R, Bird, A
Формат:	Journal article
Язык:	English
Опубликовано:	2004

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