MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex.

MeCP2 is a transcription factor that recognizes and binds symmetrically methylated CpG dinucleotides to repress transcription. MeCP2 can associate with the Sin3a/histone deacetylase corepressor complex and mediate repression in a histone deacetylase-dependent manner. In extracts from rodent tissues,...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Klose, R, Bird, A
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2004