Regression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing.

The evolution of hypertrophic cardiomyopathy (HCM) towards dilatation and hypokinesis is an increasingly recognized complication with a high incidence of adverse outcomes, including sudden cardiac death, requiring defibrillator implantation and cardiac transplantation. It is generally regarded as th...

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Main Authors: Ashrafian, H, Mason, M, Mitchell, A
Format: Journal article
Language:English
Published: 2007
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author Ashrafian, H
Mason, M
Mitchell, A
author_facet Ashrafian, H
Mason, M
Mitchell, A
author_sort Ashrafian, H
collection OXFORD
description The evolution of hypertrophic cardiomyopathy (HCM) towards dilatation and hypokinesis is an increasingly recognized complication with a high incidence of adverse outcomes, including sudden cardiac death, requiring defibrillator implantation and cardiac transplantation. It is generally regarded as the irreversible 'burnt-out' end-stage manifestation of HCM. We report one of the first cases of profound regression of the dilated-hypokinetic state by the application of biventricular pacing and cardiac resynchronization therapy (CRT). Reviewing the literature on the role of pacing in HCM and the energetic rationale for CRT in HCM prompts us to suggest that further systematic studies are needed urgently to assess the role of CRT in HCM variants.
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spelling oxford-uuid:35cb6ff9-cac4-48a2-a587-5a2cc498d0892022-03-26T13:34:03ZRegression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:35cb6ff9-cac4-48a2-a587-5a2cc498d089EnglishSymplectic Elements at Oxford2007Ashrafian, HMason, MMitchell, AThe evolution of hypertrophic cardiomyopathy (HCM) towards dilatation and hypokinesis is an increasingly recognized complication with a high incidence of adverse outcomes, including sudden cardiac death, requiring defibrillator implantation and cardiac transplantation. It is generally regarded as the irreversible 'burnt-out' end-stage manifestation of HCM. We report one of the first cases of profound regression of the dilated-hypokinetic state by the application of biventricular pacing and cardiac resynchronization therapy (CRT). Reviewing the literature on the role of pacing in HCM and the energetic rationale for CRT in HCM prompts us to suggest that further systematic studies are needed urgently to assess the role of CRT in HCM variants.
spellingShingle Ashrafian, H
Mason, M
Mitchell, A
Regression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing.
title Regression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing.
title_full Regression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing.
title_fullStr Regression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing.
title_full_unstemmed Regression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing.
title_short Regression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing.
title_sort regression of dilated hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing
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AT masonm regressionofdilatedhypokinetichypertrophiccardiomyopathybybiventricularcardiacpacing
AT mitchella regressionofdilatedhypokinetichypertrophiccardiomyopathybybiventricularcardiacpacing